Hepatopulmonary amoebiasis. Efficacy of various treatment regimens containing dehydroemetine and/or metronidazole.

Thirty three patients with hepatopulmonary amoebiasis were studied. Pulmonary involvement was observed in 55%, pleuro-pulmonary lesions in 30%. Typical chocolate coloured sputum was obtained in 24% and pleural fluid in 21% of patients. Entamoeba histolytica were demonstrable in the sputum in only 6% and in the pleural fluid in 15%. The best therapeutic results were obtained with a combination of dehydroemetine and metronidazole. However, metronidazole was found to be nearly as effective as dehydroemetine, and metronidazole 400 mg and 800 mg were equally effective.

Fascioliasis hepática

Se presentan tres pacientes procedentes de Bogotá, pertenecientes a la misma familia, consumidores habituales de berros, con cuadro clínico caracterizado por perdida de peso, dolor en hipocondrio derecho y eosinofolia causado por Fasciola hepática y confirmado por sero diagnóstico y copro-análisis. El caso estudiado en el Hospital San Juan de Dios (H.S.J.D.) sirvió como índice para el diagnóstico de los dos familiares atendidos en otras instituciones. El tratamiento se realizó con dehidroemetina en dos pacientes y en otro con praziquantel, con buenos resultados

Studies on paragonimiasis: treatment with mebendazole, emetine with mebendazole and praziquantel.

One hundred cases of paragonimiasis from Saraburi province, Thailand were studied with respect to epidemiology, clinical manifestations, radiography and treatment. Highly endemic areas were Cha-om and Sum-pugpaew villages in Kang-koy district. The ratio of male to female was 48:52. Uncooked crabs and shrimps are the second intermediate hosts of Paragonimus. Hemoptysis and chronic cough were the main symptoms; with crepitations and rhonchi in both lungs. There was no specific changes in chest X-rays of the lungs, except in cases of hemoptysis where changes in pulmonary vessels were observed. Tomograms of the lungs provided 100% accuracy and confirmation of diagnosis of pulmonary paragonimiasis. Praziquantel 25 my/kg body weight three times a day for 2 days gave a cure rate of 90%, mebendazole plus emetine hydrochloride gave a cure rate of 70% and mebendazole alone was not effective.

Absceso hepatico amibiano agudo agresivo con superinfeccion por bacilo anthrax / Acute agressive amebic hepatic abscess with Anthrax bacilus infection

Se presenta el caso de un paciente de 19 anos con un absceso hepatico amibiano superinfectado con Bacillus anthracis, asociacion no informada en la literatura. El diagnostico se hizo en base al cuadro clinico de fiebre, dolor en hipocondrio derecho, hepatomegalia y tumoracion hepatica. Se confirmo con la ecografia, anticuerpos positivos para amiba histolitica en sangre, y aislamiento del microorganismo en el pus del absceso. El tratamiento se hizo a base de metronidazol, emetina y antibioticos.

Tratamiento de las Parasitosis del aparato digestivo. / Treatment in parasitic of digestive sistem.

Se hace una actualización referente a los tratamientos delas parasitosis del aparato digestivo, poniendo énfasis en las características de los más importantes antiparasitarios y señalando los esquemas de tratamiento establecidos para cada uno de ellos.